negative regulation of GTPase activity [GO_0034260]

Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.

Tags:

Class
GO

negative regulation of GTPase activity

ID: GO_0034260

Class

Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.

An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649.

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Classification

Relationships

negatively regulates: GTPase activity

Alternative Names

Synonym	Scope	Reference
negative regulation of Ran GTPase activity	narrow synonym
down regulation of Ras GTPase activity	narrow synonym
down-regulation of regulation of Ran GTPase activity	narrow synonym	TermGenie
downregulation of Rho GTPase activity	narrow synonym
down regulation of Rab GTPase activity	narrow synonym	pf
negative regulation of Rab GTPase activity	narrow synonym
down regulation of Rho GTPase activity	narrow synonym
down-regulation of Rho GTPase activity	narrow synonym
down-regulation of Ras GTPase activity	narrow synonym
negative regulation of Ras GTPase activity	narrow synonym
down-regulation of Rab GTPase activity	narrow synonym	pf
inhibition of Ras GTPase activity	narrow synonym
downregulation of Rab GTPase activity	narrow synonym	pf
inhibition of Rab GTPase activity	narrow synonym	pf
negative regulation of Rho GTPase activity	narrow synonym
inhibition of Rho GTPase activity	narrow synonym
down regulation of regulation of Ran GTPase activity	narrow synonym	TermGenie
downregulation of Ras GTPase activity	narrow synonym
inhibition of regulation of Ran GTPase activity	narrow synonym	TermGenie
inhibition of GTPase activity	narrow synonym
downregulation of regulation of Ran GTPase activity	narrow synonym	TermGenie
negative regulation of guanosinetriphosphatase activity	exact synonym
down-regulation of GTPase activity	exact synonym
downregulation of GTPase activity	exact synonym
down regulation of GTPase activity	exact synonym

References

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an> "short_form": "GO_0003924", "label": "ARHGAP35 stimulates RHOA GTPase activity" } } ], "xrefs": [], "anatomy_channel_image": [], "pub_syn": [ { "synonym": { "scope": "has_exact_synonym", "label": "down regulation of GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "inhibition of Rho GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "negative regulation of Rho GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "negative regulation of guanosinetriphosphatase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "downregulation of GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "down-regulation of GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "negative regulation of Ran GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "negative regulation of Rab GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "inhibition of GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "down-regulation of Rho GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "downregulation of Ras GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "down regulation of Ras GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "down regulation of Rho GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "downregulation of Rho GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "negative regulation of Ras GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "down-regulation of Ras GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "inhibition of Ras GTPase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } } ], "def_pubs": [] }

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